Modulation of phosphoinositide metabolism by pathogenic bacteria

Antimicrobial Effect of Lactic Acid Bacteria against Common Pathogenic Bacteria

Abstract       Background and Objective: Probiotics are living microorganisms that have beneficial effects on the health of digestive system. The aim of this study was to evaluate the antimicrobial ability of acidic and neutral supernatants (culture supernatant) of lactic acid bacteria against common bacterial pathogens.        Meth...

Modulation of Horizontal Gene Transfer in Pathogenic Bacteria by In Vivo Signals

Here we briefly review two examples in diverse patho-gen–host systems, one well-studied and one newly-dis-*Department of Microbiology and Molecular Genetics † Shipley Institute of Medicine covered, in which bacterial DNA transfer is intimately coupled to eukaryotic host signals occurring locally at Harvard Medical School Boston, Massachusetts 02115 the site of an infection. In addition to eluci...

I28. Ammonia Production by Pathogenic Bacteria

Optogenetic control of phosphoinositide metabolism.

Phosphoinositides (PIs) are lipid components of cell membranes that regulate a wide variety of cellular functions. Here we exploited the blue light-induced dimerization between two plant proteins, cryptochrome 2 (CRY2) and the transcription factor CIBN, to control plasma membrane PI levels rapidly, locally, and reversibly. The inositol 5-phosphatase domain of OCRL (5-ptase(OCRL)), which acts on...

The Use of Aptamer in Detection of Pathogenic Bacteria-

Detection, identification and measurement of microbial pathogens is critical for protecting public health. Although microbial culture-based tests and molecular techniques are currently the most commonly used, these techniques are time-consuming and require complex tools and experienced individuals. Consequently, it is costly to analyze these techniques. The emergence of the aptamer led to the e...